Поиcк препарата по названию

Desmopressin Nasal Spray и Ibuprofen PM

Определение взаимодействия Desmopressin Nasal Spray и Ibuprofen PM и возможности их совместного приёма.

Результат проверки:

Desmopressin Nasal Spray <> Ibuprofen PM

Актуальность: 09.12.2023 Рецензент: Шкутко П.М., к.м.н., in

В базе официальных справочников, использованных при создании сервиса, найдено статистически зафиксированное результатами исследований взаимодействие, которое может либо приводить к негативным последствиям для здоровья пациента, либо усиливать взаимный положительный эффект. Требуется консультация врача для решения вопроса совместного приема лекарственных средств.

Потребитель:

Иногда ибупрофен может усиливать эффекты десмопрессина. Хотя и не часто, это может увеличить риск развития задержки воды и состояние, известное как гипонатриемия, что вызвано аномальное снижение концентрации натрия в крови. В тяжелых случаях гипонатриемия может привести к конфискации, кома или даже смерть. Вы должны обратиться к врачу, если вы испытываете потерю аппетита, тошноту, рвоту, головную боль, вялость, раздражительность, трудности с концентрацией внимания, ухудшение памяти, спутанность сознания, мышечный спазм, слабость, шаткость, снижение мочеиспускания, и/или внезапное увеличение веса, как это могут быть симптомы водной интоксикации и гипонатриемии. Важно рассказать своему врачу о всех других лекарств вы используете, в том числе витаминов и трав. Не прекратить использование любых лекарств, не посоветовавшись с врачом.

Профессионал:

Монитор: антидиуретической реакции на вазопрессин Десмопрессин или могут быть усилены определенных препаратов, включая нестероидные противовоспалительные средства, селективные ингибиторы обратного захвата серотонина, трициклические/тетрациклические антидепрессанты, карбамазепин, Хлорпропамид, аминазин, клофибрат, Eslicarbazepine, Флудрокортизон, галоперидол, ламотриджин, окскарбазепин, мочевина, а также некоторые противоопухолевые агентов (например, алкалоиды барвинка, цисплатин, циклофосфамид). Эти препараты иногда могут вызывать задержку жидкости, в некоторых случаях вторичного синдрома неадекватной секреции антидиуретического гормона (также многое другое). Одновременное применение с вазопрессином Десмопрессин или может, следовательно, увеличить риск водной интоксикации и/или гипонатриемия. Припадок и кома в связи с тяжелой гипонатриемии были зарегистрированы при одновременном применении десмопрессина и имипрамина или ибупрофена. Пожилые люди могут быть особенно чувствительны.

Управление: осторожность рекомендуется, если вазопрессина или Десмопрессин используется в сочетании с препаратами, которые могут вызвать задержка жидкости или также многое другое. Сыворотки электролитов, особенно натрия, а также Бун и креатинина следует регулярно контролировать. Пациентов следует предупредить о необходимости обратиться к врачу, если они развиваются признаки и симптомы водной интоксикации и гипонатриемии, таких как анорексия, тошнота, рвота, головная боль, недомогание, вялость, раздражительность, трудности с концентрацией внимания, ухудшение памяти, спутанность сознания, слабость, спазм мышц, шаткость (что может привести к падениям), анурия, и увеличение веса. Раннее лечение может помочь предотвратить прогрессирование захват, кома, остановка дыхания и смерть.

Источники

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