Dolobid и Pioglitazone and Glimepiride Tablets
Определение взаимодействия Dolobid и Pioglitazone and Glimepiride Tablets и возможности их совместного приёма.
В базе официальных справочников, использованных при создании сервиса, найдено статистически зафиксированное результатами исследований взаимодействие, которое может либо приводить к негативным последствиям для здоровья пациента, либо усиливать взаимный положительный эффект. Требуется консультация врача для решения вопроса совместного приема лекарственных средств.
Потребитель:Дифлунизал может усиливать действие глимепирида и вызвать ваш уровень сахара в крови слишком низкий. Симптомы низкого уровня сахара в крови включают головную боль, головокружение, сонливость, тошнота, голод, Тремор, слабость, потливость, быстрый или стучать сердцебиений. Поговорите с вашим врачом, прежде чем использовать эти препараты вместе. Вам может понадобиться регулировки дозы или более частого контроля сахара в крови, если вы используете глимепирида и начинают лечение с дифлунизал. Важно рассказать своему врачу о всех других лекарств вы используете, в том числе витаминов и трав. Не прекратить использование любых лекарств, не посоветовавшись с врачом.
Профессионал:Монитор: гипогликемический эффект инсулина секретагоги (например, производные сульфонилмочевины, меглитиниды) могут быть усилены определенных препаратов, включая ингибиторы АПФ, аналоги амилина, анаболические стероиды, фибраты, ингибиторы моноаминоксидазы (ингибиторы МАО, включая линезолид), нестероидные противовоспалительные препараты (НПВП), салицилаты, ингибиторы обратного захвата серотонина (СИОЗС), сульфаниламиды, дизопирамид, пропоксифена, хинин, хинидин, и женьшеня. Эти препараты могут увеличивать риск развития гипогликемии за счет повышения чувствительности к инсулину (ингибиторы АПФ, фибратов, женьшень); стимулирующие секрецию инсулина (салицилаты, нестероидные противовоспалительные средства, дизопирамид, хинина, хинидина, ингибиторов МАО, женьшень); повышение периферической утилизации глюкозы (СИОЗС, инсулиноподобный фактор роста); ингибирования глюконеогенеза (СИОЗС, ингибиторы МАО, инсулин-подобный фактор роста); замедление опорожнения желудка (аналоги амилина); и/или подавление постпрандиальной секреции глюкагона (аналоги амилина). Или, они могут повышать плазменную концентрацию секретагоги инсулина путем вытеснения их из плазмы связывания белка и/или ингибирования их метаболизма (фибраты, НПВС, салицилаты, сульфаниламиды). Клинические гипогликемии отмечается при использовании некоторых из этих агентов в одиночку или с инсулином и/или сульфонилмочевины. Использование СИОЗС также было связано с потерей сознания гипогликемии в отдельных случаях.
Управление: тщательный мониторинг развития гипогликемии рекомендуется, если эти препараты применяться одновременно с секретагоги инсулина, особенно у больных преклонного возраста и/или почечной недостаточностью. Устные дозировка антидиабетических(S) может потребовать корректировки, если взаимодействие подозревается. Пациенты должны быть проинформированы о признаках и симптомах гипогликемии (например, головная боль, головокружение, сонливость, тошнота, голод, Тремор, слабость, потливость, сердцебиение), как это лечить, и связаться их врачом, если это происходит. Пациенты должны быть соблюдены для потери гликемического контроля, когда эти препараты изъяты.
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Непатентованное наименование: diflunisal
Торговая марка: Dolobid
Синонимы: нет
Непатентованное наименование: glimepiride / pioglitazone
Торговая марка: Duetact
Синонимы: Glimepiride and pioglitazone, Pioglitazone and Glimepiride
В процессе проверки совместимости и взаимодействий лекарств используются данные справочников: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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